Concerns regarding universal varicella immunization. Time will tell
L. L. MacFarlane, M. L. Sanders and P. J. Carek
Department of Family Medicine, Medical University of South Carolina, Charleston, USA. macfarll@musc.edu
The American Academy of Pediatrics, the Advisory Committee on Immunization
Practices, and the American Academy of Family Physicians now recommend
universal immunization for varicella for all susceptible children and
adolescents. Although the varicella vaccine appears safe and efficacious,
it is unknown how universal immunization will influence the epidemiology of
varicella infections. The duration of immunity, both conferred and passive
reinoculation, remains a concern and must continue to be evaluated in the
population of vaccinees. As universal immunization is implemented, the
cost-effectiveness of such a program will need to be evaluated. Physicians
and parents must be educated about the risks and benefits of vaccination vs
natural infection.
